Synthesis and Antimicrobial Analysis of High Surface Area Strontium-Substituted Calcium Phosphate Nanostructures for Bone Regeneration

Continuous microwave-assisted flow synthesis has been used as a simple, more efficient, and low-cost route to fabricate range of nanosized (<100 nm) strontium-substituted calcium phosphates. In this study, fine nanopowder was synthesized via continuous with microwave assistance from the solutions nitrate tetrahydrate (with strontium Sr2+ ion source) diammonium hydrogen phosphate at pH 10 time duration 5 min. The morphological characterization obtained powder carried out by employing techniques such transmission electron microscopy, X-ray diffraction, Brunauer–Emmett–Teller surface area analysis. chemical structural analysis evaluate properties made using photoelectron spectroscopy. Zeta potential performed colloidal stability particles. Antimicrobial studies were for all compositions four bacterial strains an opportunistic human fungal pathogen Macrophomina phaseolina. It found that nanoproduct high content (15 wt% strontium) showed pronounced antibacterial against M. luteus while it completely arrested growth after 48 h its concentrations. Thus strategy described herein facilitated rapid production Sr-substituted CaPs excellent biological performance suitable bone replacement application.